I have been working as a Principal Statistician at UCLA since 2012. I have broad interests in medical research, and my experience includes: model building for linear and non-linear models, Bayesian hierarchical models, microarray data analysis, principal components analysis, hierarchical clustering and heatmaps, network analysis, clinical data management and analysis, and meta-analysis. I am also interested in working on bioinformatics projects using Next Generation Sequencing data.
Duan L. and Thomas DC. A Bayesian hierarchical model for relating multiple SNPs with multiple genes to disease risk. International Journal of Genomics. In press. Machida K, Liu JC, McNamara G, Levine A, Duan L, Lai MM. Hepatitis C virus causes uncoupling of mitotic checkpoint and chromosomal polyploidy through the Rb pathway. J Virol. 2009 Dec;83(23):12590-600. doi: 10.1128/JVI.02643-08. Epub 2009 Sep 30.
Machida K, Tsukamoto H, Mkrtchyan H, Duan L, Dynnyk A, Liu HM, Asahina K, Govindarajan S, Ray R, Ou JH, Seki E, Deshaies R, Miyake K, Lai MM. Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1548-53. doi: 10.1073/pnas.0807390106. Epub 2009 Jan 26.